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Minocycline corrects early, pre-plaque neuroinflammation and inhibits BACE-1 in a transgenic model of Alzheimer's disease-like amyloid pathology

<p>Abstract</p> <p>Background</p> <p>A growing body of evidence indicates that inflammation is one of the earliest neuropathological events in Alzheimer's disease. Accordingly, we have recently shown the occurrence of an early, pro-inflammatory reaction in the hipp...

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Main Authors: Ferretti Maria, Allard Simon, Partridge Vanessa, Ducatenzeiler Adriana, Cuello A Claudio
格式: Artigo
語言:Inglês
出版: BMC 2012-04-01
叢編:Journal of Neuroinflammation
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在線閱讀:http://www.jneuroinflammation.com/content/9/1/62
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