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3-Hydroxy-3-Methylglutaryl-COA Reductase Inhibitors and Phosphodiesterase Type V Inhibitors Attenuate Right Ventricular Pressure and Remodeling in a Rat Model of Pulmonary Hypertension

PURPOSE. We examined the inhibitory effects of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors and a phosphodiesterase type V inhibitor on hemodynamic function and cardiac remodeling in rats with monocrotaline-induced pulmonary hypertension. METHODS. The rat model of pulmonary hypertensi...

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Detalhes bibliográficos
Main Authors: Mitsutoshi Satoh, Akira Satoh
Formato: Artigo
Idioma:Inglês
Publicado em: Canadian Society for Pharmaceutical Sciences 2009-02-01
Colecção:Journal of Pharmacy & Pharmaceutical Sciences
Acesso em linha:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/4068
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