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3-Hydroxy-3-Methylglutaryl-COA Reductase Inhibitors and Phosphodiesterase Type V Inhibitors Attenuate Right Ventricular Pressure and Remodeling in a Rat Model of Pulmonary Hypertension
PURPOSE. We examined the inhibitory effects of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors and a phosphodiesterase type V inhibitor on hemodynamic function and cardiac remodeling in rats with monocrotaline-induced pulmonary hypertension. METHODS. The rat model of pulmonary hypertensi...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Canadian Society for Pharmaceutical Sciences
2009-02-01
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Colecção: | Journal of Pharmacy & Pharmaceutical Sciences |
Acesso em linha: | https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/4068 |
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