Formalin-Fixed Paraffin-Embedded Tissues—An Untapped Biospecimen for Biomonitoring DNA Adducts by Mass Spectrometry

The measurement of DNA adducts provides important information about human exposure to genotoxic chemicals and can be employed to elucidate mechanisms of DNA damage and repair. DNA adducts can serve as biomarkers for interspecies comparisons of the biologically effective dose of procarcinogens and pe...

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Bibliographic Details
Main Authors: Byeong Hwa Yun, Jingshu Guo, Robert J. Turesky
Format: Artigo
Language:Inglês
Published: MDPI AG 2018-06-01
Series:Toxics
Subjects:
carcinogen
DNA adducts
biomonitoring
formalin-fixed paraffin-embedded tissues
biomarker
mass spectrometry
Online Access:http://www.mdpi.com/2305-6304/6/2/30
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