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DNA Adducts: formation, biological effects, and new biospecimens for mass spectrometric measurements in humans
Hazardous chemicals in the environment and diet or their electrophilic metabolites can form adducts with genomic DNA, which can lead to mutations and the initiation of cancer. In addition, reactive intermediates can be generated in the body through oxidative stress and damage the genome. The identif...
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| Publié dans: | Mass Spectrom Rev |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6289887/ https://ncbi.nlm.nih.gov/pubmed/29889312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mas.21570 |
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