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Mechanisms of Disulfide Bond Formation in Nascent Polypeptides Entering the Secretory Pathway

Disulphide bonds are an abundant feature of proteins across all domains of life that are important for structure, stability, and function. In eukaryotic cells, a major site of disulphide bond formation is the endoplasmic reticulum (ER). How cysteines correctly pair during polypeptide folding to form...

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Bibliografske podrobnosti
Main Authors: Philip J. Robinson, Neil J. Bulleid
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2020-08-01
Serija:Cells
Teme:
PDI
ER
Online dostop:https://www.mdpi.com/2073-4409/9/9/1994
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