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Mechanisms of Disulfide Bond Formation in Nascent Polypeptides Entering the Secretory Pathway

Disulfide bonds are an abundant feature of proteins across all domains of life that are important for structure, stability, and function. In eukaryotic cells, a major site of disulfide bond formation is the endoplasmic reticulum (ER). How cysteines correctly pair during polypeptide folding to form t...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Robinson, Philip J., Bulleid, Neil J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7565403/
https://ncbi.nlm.nih.gov/pubmed/32872499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9091994
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