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Mechanisms of Disulfide Bond Formation in Nascent Polypeptides Entering the Secretory Pathway

Disulphide bonds are an abundant feature of proteins across all domains of life that are important for structure, stability, and function. In eukaryotic cells, a major site of disulphide bond formation is the endoplasmic reticulum (ER). How cysteines correctly pair during polypeptide folding to form...

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Sonraí Bibleagrafaíochta
Main Authors: Philip J. Robinson, Neil J. Bulleid
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI AG 2020-08-01
Sraith:Cells
Ábhair:
PDI
ER
Rochtain Ar Líne:https://www.mdpi.com/2073-4409/9/9/1994
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