Replication independent DNA double-strand break retention may prevent genomic instability

<p>Abstract</p> <p>Background</p> <p>Global hypomethylation and genomic instability are cardinal features of cancers. Recently, we established a method for the detection of DNA methylation levels at sites close to endogenous DNA double strand breaks (EDSBs), and found t...

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Bibliografiska uppgifter
Huvudupphovsmän: Pornthanakasem Wichai, Rattanatanyong Prakasit, Ponyeam Wanpen, Thongnak Araya, Phuangphairoj Chutipa, Kongruttanachok Narisorn, Mutirangura Apiwat
Materialtyp: Artigo
Språk:Inglês
Publicerad: BMC 2010-03-01
Serie:Molecular Cancer
Länkar:http://www.molecular-cancer.com/content/9/1/70
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