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A Mononucleotide Markers Panel to Identify hMLH1/hMSH2 Germline Mutations
Hereditary NonPolyposis Colorectal Cancer (Lynch syndrome) is an autosomal dominant disease caused by germline mutations in a class of genes deputed to maintain genomic integrity during cell replication, mutations result in a generalized genomic instability, particularly evident at microsatellite lo...
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Main Authors: | , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Hindawi Limited
2007-01-01
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Colecção: | Disease Markers |
Acesso em linha: | http://dx.doi.org/10.1155/2007/703129 |
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