Heme activates TLR4-mediated inflammatory injury via MyD88/TRIF signaling pathway in intracerebral hemorrhage

<p>Abstract</p> <p>Background</p> <p>Inflammatory injury plays a critical role in intracerebral hemorrhage (ICH)-induced neurological deficits; however, the signaling pathways are not apparent by which the upstream cellular events trigger innate immune and inflammatory...

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Autori principali: Lin Sen, Yin Qing, Zhong Qi, Lv Feng-Lin, Zhou Yu, Li Jing-Qi, Wang Jing-Zhou, Su Bing-yin, Yang Qing-Wu
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2012-03-01
Serie:Journal of Neuroinflammation
Soggetti:
Toll-like receptor 4
MyD88
TRIF
Inflammation
Intracerebral hemorrhage
Heme
Accesso online:http://www.jneuroinflammation.com/content/9/1/46
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