Heme activates TLR4-mediated inflammatory injury via MyD88/TRIF signaling pathway in intracerebral hemorrhage

BACKGROUND: Inflammatory injury plays a critical role in intracerebral hemorrhage (ICH)-induced neurological deficits; however, the signaling pathways are not apparent by which the upstream cellular events trigger innate immune and inflammatory responses that contribute to neurological impairments....

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Detalhes bibliográficos
Main Authors: Lin, Sen, Yin, Qing, Zhong, Qi, Lv, Feng-Lin, Zhou, Yu, Li, Jing-Qi, Wang, Jing-Zhou, Su, Bing-yin, Yang, Qing-Wu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3344687/
https://ncbi.nlm.nih.gov/pubmed/22394415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-46
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