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Simvastatin improves intracerebral hemorrhage through NF-κB-mediated apoptosis via the MyD88/TRIF signaling pathway

The aim was to investigate the neuroprotective effects and potential mechanism mediated by simvastatin in a mouse model of intracerebral hemorrhage. CD-1 mice were subjected to infusion of collagenase type IV into the left striatum in order to induce intracerebral hemorrhage. Western blot analysis,...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: Gu, Chengyao, Wu, Yunqin, Fan, Zhenyi, Han, Weiwei
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5763742/
https://ncbi.nlm.nih.gov/pubmed/29375693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.5349
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