Fast Alpha Activity in EEG of Patients With Alzheimer’s Disease Is Paralleled by Changes in Cognition and Cholinergic Markers During Encapsulated Cell Biodelivery of Nerve Growth Factor

BackgroundBasal forebrain cholinergic neurons are dependent on nerve growth factor (NGF) for growth and survival and these cells are among the first to degenerate in Alzheimer’s disease (AD). Targeted delivery of NGF has been suggested as a potential therapy for AD. This hypothesis was tested in a c...

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Main Authors: Helga Eyjolfsdottir, Thomas Koenig, Azadeh Karami, Per Almqvist, Göran Lind, Bengt Linderoth, Lars Wahlberg, Åke Seiger, Taher Darreh-Shori, Maria Eriksdotter, Vesna Jelic
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-04-01
Colecção:Frontiers in Aging Neuroscience
Assuntos:
EEG
EEG alpha activity
Alzheimer’s disease
nerve growth factor
encapsulated cell biodelivery
choline acetyltransferase
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fnagi.2022.756687/full
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