CSF Cholinergic Index, a New Biomeasure of Treatment Effect in Patients With Alzheimer’s Disease

Alzheimer’s disease (AD) is a progressive disease with early degeneration of the central cholinergic neurons. Currently, three of four AD drugs act by inhibiting the acetylcholine (ACh) degrading enzyme, acetylcholinesterase (AChE). Efficacy of these drugs depends on available amount of ACh, which i...

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Bibliografski detalji
Izdano u:Front Mol Neurosci
Glavni autori: Karami, Azadeh, Eriksdotter, Maria, Kadir, Ahmadul, Almkvist, Ove, Nordberg, Agneta, Darreh-Shori, Taher
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Neuroscience
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798072/
https://ncbi.nlm.nih.gov/pubmed/31680850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2019.00239
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