CSF Cholinergic Index, a New Biomeasure of Treatment Effect in Patients With Alzheimer’s Disease

Alzheimer’s disease (AD) is a progressive disease with early degeneration of the central cholinergic neurons. Currently, three of four AD drugs act by inhibiting the acetylcholine (ACh) degrading enzyme, acetylcholinesterase (AChE). Efficacy of these drugs depends on available amount of ACh, which i...

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Detaylı Bibliyografya
Yayımlandı:Front Mol Neurosci
Asıl Yazarlar: Karami, Azadeh, Eriksdotter, Maria, Kadir, Ahmadul, Almkvist, Ove, Nordberg, Agneta, Darreh-Shori, Taher
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2019
Konular:
Neuroscience
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798072/
https://ncbi.nlm.nih.gov/pubmed/31680850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2019.00239
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