CSF Cholinergic Index, a New Biomeasure of Treatment Effect in Patients With Alzheimer’s Disease

Alzheimer’s disease (AD) is a progressive disease with early degeneration of the central cholinergic neurons. Currently, three of four AD drugs act by inhibiting the acetylcholine (ACh) degrading enzyme, acetylcholinesterase (AChE). Efficacy of these drugs depends on available amount of ACh, which i...

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Détails bibliographiques
Publié dans:Front Mol Neurosci
Auteurs principaux: Karami, Azadeh, Eriksdotter, Maria, Kadir, Ahmadul, Almkvist, Ove, Nordberg, Agneta, Darreh-Shori, Taher
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Neuroscience
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798072/
https://ncbi.nlm.nih.gov/pubmed/31680850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2019.00239
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