Targeted delivery of nerve growth factor to the cholinergic basal forebrain of Alzheimer’s disease patients: application of a second-generation encapsulated cell biodelivery device

BACKGROUND: Targeted delivery of nerve growth factor (NGF) has emerged as a potential therapy for Alzheimer’s disease (AD) due to its regenerative effects on basal forebrain cholinergic neurons. This hypothesis has been tested in patients with AD using encapsulated cell biodelivery of NGF (NGF-ECB)...

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Detalhes bibliográficos
Publicado no:Alzheimers Res Ther
Main Authors: Eyjolfsdottir, Helga, Eriksdotter, Maria, Linderoth, Bengt, Lind, Göran, Juliusson, Bengt, Kusk, Philip, Almkvist, Ove, Andreasen, Niels, Blennow, Kaj, Ferreira, Daniel, Westman, Eric, Nennesmo, Inger, Karami, Azadeh, Darreh-Shori, Taher, Kadir, Ahmadul, Nordberg, Agneta, Sundström, Erik, Wahlund, Lars-Olof, Wall, Anders, Wiberg, Maria, Winblad, Bengt, Seiger, Åke, Wahlberg, Lars, Almqvist, Per
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936020/
https://ncbi.nlm.nih.gov/pubmed/27389402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-016-0195-9
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