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RIG-I overexpression decreases mortality of cigarette smoke exposed mice during influenza A virus infection
Abstract Background Retinoic acid-inducible gene I (RIG-I) is an important regulator of virus-induced antiviral interferons (IFNs) and proinflammatory cytokines which participate in clearing viral infections. Cigarette smoke (CS) exposure increases the frequency and severity of respiratory tract inf...
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Main Authors: | , , , , , , , , , , , |
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格式: | Artigo |
語言: | Inglês |
出版: |
BMC
2017-09-01
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叢編: | Respiratory Research |
主題: | |
在線閱讀: | http://link.springer.com/article/10.1186/s12931-017-0649-z |
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