RIG-I overexpression decreases mortality of cigarette smoke exposed mice during influenza A virus infection

Abstract Background Retinoic acid-inducible gene I (RIG-I) is an important regulator of virus-induced antiviral interferons (IFNs) and proinflammatory cytokines which participate in clearing viral infections. Cigarette smoke (CS) exposure increases the frequency and severity of respiratory tract inf...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Xiaoqiu Wang, Wenxin Wu, Wei Zhang, J. Leland Booth, Elizabeth S. Duggan, Lili Tian, Sunil More, Yan D. Zhao, Ravindranauth N. Sawh, Lin Liu, Ming-Hui Zou, Jordan P. Metcalf
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMC 2017-09-01
Cyfres:Respiratory Research
Pynciau:
Influenza virus
Lung
Smoking
Cytokine
RIG-I
Transgenic mouse
Mynediad Ar-lein:http://link.springer.com/article/10.1186/s12931-017-0649-z
Tagiau: Ychwanegu Tag
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