Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains.

In embryonic stem (ES) cells, bivalent chromatin domains with overlapping repressive (H3 lysine 27 tri-methylation) and activating (H3 lysine 4 tri-methylation) histone modifications mark the promoters of more than 2,000 genes. To gain insight into the structure and function of bivalent domains, we...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Manching Ku, Richard P Koche, Esther Rheinbay, Eric M Mendenhall, Mitsuhiro Endoh, Tarjei S Mikkelsen, Aviva Presser, Chad Nusbaum, Xiaohui Xie, Andrew S Chi, Mazhar Adli, Simon Kasif, Leon M Ptaszek, Chad A Cowan, Eric S Lander, Haruhiko Koseki, Bradley E Bernstein
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2008-10-01
Serija:PLoS Genetics
Online dostop:http://europepmc.org/articles/PMC2567431?pdf=render
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki