Late-onset of spinal neurodegeneration in knock-in mice expressing a mutant BiP.

Por Hisayo Jin, Naoya Mimura, Makiko Kashio, Haruhiko Koseki, Tomohiko Aoe
Publicado em 2014-01-01

Requirement of Stat3 Signaling in the Postnatal Development of Thymic Medullary Epithelial Cells.

Por Rumi Satoh, Kiyokazu Kakugawa, Takuwa Yasuda, Hisahiro Yoshida, Maria Sibilia, Yoshimoto Katsura, Ben Levi, Jakub Abramson, Yoko Koseki, Haruhiko Koseki, Willem van Ewijk, Georg A Hollander, Hiroshi Kawamoto
Publicado em 2016-01-01

Histone H2A mono-ubiquitination is a crucial step to mediate PRC1-dependent repression of developmental genes to maintain ES cell identity.

Por Mitsuhiro Endoh, Takaho A Endo, Tamie Endoh, Kyo-ichi Isono, Jafar Sharif, Osamu Ohara, Tetsuro Toyoda, Takashi Ito, Ragnhild Eskeland, Wendy A Bickmore, Miguel Vidal, Bradley E Bernstein, Haruhiko Koseki
Publicado em 2012-01-01

DNMTs and SETDB1 function as co-repressors in MAX-mediated repression of germ cell-related genes in mouse embryonic stem cells.

Por Daiki Tatsumi, Yohei Hayashi, Mai Endo, Hisato Kobayashi, Takumi Yoshioka, Kohei Kiso, Shinichiro Kanno, Yuji Nakai, Ikuma Maeda, Kentaro Mochizuki, Makoto Tachibana, Haruhiko Koseki, Akihiko Okuda, Akira Yasui, Tomohiro Kono, Yasuhisa Matsui
Publicado em 2018-01-01

Lack of whey acidic protein (WAP) four-disulfide core domain protease inhibitor 2 (WFDC2) causes neonatal death from respiratory failure in mice

Por Kuniko Nakajima, Michio Ono, Uroš Radović, Selma Dizdarević, Shin-ichi Tomizawa, Kazushige Kuroha, Go Nagamatsu, Ikue Hoshi, Risa Matsunaga, Takayuki Shirakawa, Takeyuki Kurosawa, Yasunari Miyazaki, Masahide Seki, Yutaka Suzuki, Haruhiko Koseki, Masataka Nakamura, Toshio Suda, Kazuyuki Ohbo
Publicado em 2019-11-01

Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains.

Por Manching Ku, Richard P Koche, Esther Rheinbay, Eric M Mendenhall, Mitsuhiro Endoh, Tarjei S Mikkelsen, Aviva Presser, Chad Nusbaum, Xiaohui Xie, Andrew S Chi, Mazhar Adli, Simon Kasif, Leon M Ptaszek, Chad A Cowan, Eric S Lander, Haruhiko Koseki, Bradley E Bernstein
Publicado em 2008-10-01

Zinc Transporter SLC39A7/ZIP7 Promotes Intestinal Epithelial Self-Renewal by Resolving ER Stress.

Por Wakana Ohashi, Shunsuke Kimura, Toshihiko Iwanaga, Yukihiro Furusawa, Tarou Irié, Hironori Izumi, Takashi Watanabe, Atsushi Hijikata, Takafumi Hara, Osamu Ohara, Haruhiko Koseki, Toshiro Sato, Sylvie Robine, Hisashi Mori, Yuichi Hattori, Hiroshi Watarai, Kenji Mishima, Hiroshi Ohno, Koji Hase, Toshiyuki Fukada
Publicado em 2016-10-01

Smchd1 Targeting to the Inactive X Is Dependent on the Xist-HnrnpK-PRC1 Pathway

Por Natasha Jansz, Tatyana Nesterova, Andrew Keniry, Megan Iminitoff, Peter F. Hickey, Greta Pintacuda, Osamu Masui, Simon Kobelke, Niall Geoghegan, Kelsey A. Breslin, Tracy A. Willson, Kelly Rogers, Graham F. Kay, Archa H. Fox, Haruhiko Koseki, Neil Brockdorff, James M. Murphy, Marnie E. Blewitt
Publicado em 2018-11-01