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Cell type-specific function of TRAF2 and TRAF3 in regulating type I IFN induction

Abstract Background TRAF3 is known as a central mediator of type I interferon (IFN) induction by various pattern recognition receptors, but the in vivo function of TRAF3 in host defense against viral infection is poorly defined due to the lack of a viable mouse model. Results Here we show that mice...

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Bibliografische gegevens
Hoofdauteurs: Xiaoping Xie, Jin Jin, Lele Zhu, Zuliang Jie, Yanchuan Li, Baoyu Zhao, Xuhong Cheng, Pingwei Li, Shao-Cong Sun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMC 2019-01-01
Reeks:Cell & Bioscience
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Online toegang:http://link.springer.com/article/10.1186/s13578-018-0268-5
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