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Cell type-specific function of TRAF2 and TRAF3 in regulating type I IFN induction
Abstract Background TRAF3 is known as a central mediator of type I interferon (IFN) induction by various pattern recognition receptors, but the in vivo function of TRAF3 in host defense against viral infection is poorly defined due to the lack of a viable mouse model. Results Here we show that mice...
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Hoofdauteurs: | , , , , , , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
BMC
2019-01-01
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Reeks: | Cell & Bioscience |
Onderwerpen: | |
Online toegang: | http://link.springer.com/article/10.1186/s13578-018-0268-5 |
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