Cell type-specific function of TRAF2 and TRAF3 in regulating type I IFN induction

BACKGROUND: TRAF3 is known as a central mediator of type I interferon (IFN) induction by various pattern recognition receptors, but the in vivo function of TRAF3 in host defense against viral infection is poorly defined due to the lack of a viable mouse model. RESULTS: Here we show that mice carryin...

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Bibliographic Details
Published in:Cell Biosci
Main Authors: Xie, Xiaoping, Jin, Jin, Zhu, Lele, Jie, Zuliang, Li, Yanchuan, Zhao, Baoyu, Cheng, Xuhong, Li, Pingwei, Sun, Shao-Cong
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318904/
https://ncbi.nlm.nih.gov/pubmed/30622699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-018-0268-5
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