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Viral sequestration of antigen subverts cross presentation to CD8(+) T cells.
Virus-specific CD8(+) T cells (T(CD8+)) are initially triggered by peptide-MHC Class I complexes on the surface of professional antigen presenting cells (pAPC). Peptide-MHC complexes are produced by two spatially distinct pathways during virus infection. Endogenous antigens synthesized within virus-...
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| Main Authors: | , , , , , , , |
|---|---|
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science (PLoS)
2009-05-01
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| 叢編: | PLoS Pathogens |
| 在線閱讀: | http://europepmc.org/articles/PMC2680035?pdf=render |
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