QR Kod

89Zr-mAb uptake interpretation requires the use of tissue to plasma ratios corrected for antibody catabolism

Abstract Background Typically, tissue uptake, expressed in tissue over plasma ratio (TPR), is reported from a 89Zr-mAb PET study. Nonspecific antibody catabolism and the residualizing property of 89Zr hamper the use of tissue uptake as a measure for target mediated uptake. Therefore, we propose to r...

Ful tanımlama

Kaydedildi:
Asıl Yazarlar: Marc C. Huisman, Johanna E. E. Pouw, Sandeep S. V. Golla, Damien Huglo, Franck Morschhauser, Josée M. Zijlstra, Jessica E. Wijngaarden, Mirte Stavenga, Hylke J. Sebus, Maarten Slebe, Andrea Thiele, Danielle Vugts, Iris H. C. Miedema, Gerben J.C. Zwezerijnen, Idris Bahce, C. Willemien Menke-van der Houven van Oordt, Dhaval K. Shah, Yvonne W. S. Jauw, Ronald Boellaard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: SpringerOpen 2025-09-01
Seri Bilgileri:EJNMMI Research
Konular:
89Zr-mAb
89Zr-immuno-PET
Quantification
Online Erişim:https://doi.org/10.1186/s13550-025-01315-6
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller