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How to obtain the image-derived blood concentration from 89Zr-immuno-PET scans

Abstract Background PET scans using zirconium-89 labelled monoclonal antibodies (89Zr-mAbs), known as 89Zr-immuno-PET, are made to measure uptake in tumour and organ tissue. Uptake is related to the supply of 89Zr-mAbs in the blood. Measuring activity concentrations in blood, however, requires invas...

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Principais autores: Jessica E. Wijngaarden, Amina Ahbari, Johanna E. E. Pouw, Henri N. J. M. Greuter, Idris Bahce, Gerben J. C. Zwezerijnen, Daniëlle J. Vugts, Guus A. M. S. van Dongen, Ronald Boellaard, C. Willemien Menke-van der Houven van Oordt, Marc C. Huisman
Formato: Artigo
Idioma:Inglês
Publicado em: SpringerOpen 2024-02-01
coleção:EJNMMI Physics
Assuntos:
89Zr-immuno-PET
Blood sampling
Image-derived blood concentration
Monoclonal antibodies
Acesso em linha:https://doi.org/10.1186/s40658-024-00621-7
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