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NAA-modified DNA oligonucleotides with zwitterionic backbones: stereoselective synthesis of A–T phosphoramidite building blocks

Modifications of the nucleic acid backbone are essential for the development of oligonucleotide-derived bioactive agents. The NAA-modification represents a novel artificial internucleotide linkage which enables the site-specific introduction of positive charges into the otherwise polyanionic backbon...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Boris Schmidtgall, Claudia Höbartner, Christian Ducho
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Beilstein-Institut 2015-01-01
Saila:Beilstein Journal of Organic Chemistry
Gaiak:
Sarrera elektronikoa:https://doi.org/10.3762/bjoc.11.8
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