क्यूआर कोड

In Silico Identification of 2,4-Diaminopyrimidine-Based Compounds as Potential CK1ε Inhibitors

<b>Background:</b> Casein kinase 1 epsilon (CK1ε) plays a critical role in cancer progression by activating oncogenic signaling pathways, making it a target for cancer therapy. However, no inhibitors are currently available for clinical use, highlighting the need for novel therapeutic candidates. <b...

पूर्ण विवरण

में बचाया:
मुख्य लेखकों: Axel A. Sánchez-Álvarez, Marco A. Velasco-Velázquez, Luis Cordova-Bahena
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI AG 2025-05-01
श्रृंखला:Pharmaceuticals
विषय:
CK1ε
cancer
virtual screening
diaminopyrimidine
molecular dynamic simulations
pharmacophore model
ऑनलाइन पहुंच:https://www.mdpi.com/1424-8247/18/5/741
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