In Silico Identification of 2,4-Diaminopyrimidine-Based Compounds as Potential CK1ε Inhibitors

<b>Background:</b> Casein kinase 1 epsilon (CK1ε) plays a critical role in cancer progression by activating oncogenic signaling pathways, making it a target for cancer therapy. However, no inhibitors are currently available for clinical use, highlighting the need for novel therapeutic candidates. <b...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Axel A. Sánchez-Álvarez, Marco A. Velasco-Velázquez, Luis Cordova-Bahena
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2025-05-01
Цуврал:	Pharmaceuticals
Нөхцлүүд:	CK1ε cancer virtual screening diaminopyrimidine molecular dynamic simulations pharmacophore model
Онлайн хандалт:	https://www.mdpi.com/1424-8247/18/5/741
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!