Unraveling a novel therapeutic facet of Etravirine to confront Hepatocellular Carcinoma via disruption of cell cycle

Abstract Hepatocellular Carcinoma (HCC) is a malignancy with high mortality rates and limited treatment options. This study aimed to unearth the repurposable potential of FDA-approved drugs against specific genetic targets governing the HCC pathological pathways. The transcriptomics microarray datas...

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Bibliografische Detailangaben

Hauptverfasser:	Gouri Nair, G. R. Saraswathy, Jesil Mathew Aranjani, Rafwana Ibrahim
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2025-02-01
Schriftenreihe:	Scientific Reports
Schlagworte:	Hepatocellular Carcinoma Drug repurposing CCNA2 CDK1 CDK2 Etravirine
Online-Zugang:	https://doi.org/10.1038/s41598-025-87676-3
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