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Unraveling a novel therapeutic facet of Etravirine to confront Hepatocellular Carcinoma via disruption of cell cycle

Abstract Hepatocellular Carcinoma (HCC) is a malignancy with high mortality rates and limited treatment options. This study aimed to unearth the repurposable potential of FDA-approved drugs against specific genetic targets governing the HCC pathological pathways. The transcriptomics microarray datas...

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Wedi'i Gadw mewn:
Prif Awduron: Gouri Nair, G. R. Saraswathy, Jesil Mathew Aranjani, Rafwana Ibrahim
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Portfolio 2025-02-01
Cyfres:Scientific Reports
Pynciau:
Hepatocellular Carcinoma
Drug repurposing
CCNA2
CDK1
CDK2
Etravirine
Mynediad Ar-lein:https://doi.org/10.1038/s41598-025-87676-3
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