Unraveling a novel therapeutic facet of Etravirine to confront Hepatocellular Carcinoma via disruption of cell cycle

Abstract Hepatocellular Carcinoma (HCC) is a malignancy with high mortality rates and limited treatment options. This study aimed to unearth the repurposable potential of FDA-approved drugs against specific genetic targets governing the HCC pathological pathways. The transcriptomics microarray datas...

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Autores principales:	Gouri Nair, G. R. Saraswathy, Jesil Mathew Aranjani, Rafwana Ibrahim
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Portfolio 2025-02-01
Colección:	Scientific Reports
Materias:	Hepatocellular Carcinoma Drug repurposing CCNA2 CDK1 CDK2 Etravirine
Acceso en línea:	https://doi.org/10.1038/s41598-025-87676-3
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