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In Silico Identification of 2,4-Diaminopyrimidine-Based Compounds as Potential CK1ε Inhibitors

<b>Background:</b> Casein kinase 1 epsilon (CK1ε) plays a critical role in cancer progression by activating oncogenic signaling pathways, making it a target for cancer therapy. However, no inhibitors are currently available for clinical use, highlighting the need for novel therapeutic candidates. <b...

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主要な著者: Axel A. Sánchez-Álvarez, Marco A. Velasco-Velázquez, Luis Cordova-Bahena
フォーマット: Artigo
言語:Inglês
出版事項: MDPI AG 2025-05-01
シリーズ:Pharmaceuticals
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オンライン・アクセス:https://www.mdpi.com/1424-8247/18/5/741
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