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A Comprehensive Physiologically Based Pharmacokinetic Model of Nadolol in Adults with Renal Disease and Pediatrics with Supraventricular Tachycardia

Nadolol is a long-acting non-selective β–adrenergic antagonist that helps treat angina and hypertension. The current study aimed to develop and validate the physiologically based pharmacokinetic model (PBPK) of nadolol in healthy adults, renal-compromised, and pediatric populations. A comprehensive...

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Principais autores: Samia Kalsoom, Muhammad Fawad Rasool, Imran Imran, Hamid Saeed, Tanveer Ahmad, Faleh Alqahtani
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2024-02-01
Serier:Pharmaceuticals
Fag:
nadolol
physiologically based pharmacokinetic
PK-Sim
pharmacokinetic
renal impairment
pediatrics
Online adgang:https://www.mdpi.com/1424-8247/17/2/265
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