A Comprehensive Physiologically Based Pharmacokinetic Model of Nadolol in Adults with Renal Disease and Pediatrics with Supraventricular Tachycardia

Nadolol is a long-acting non-selective β–adrenergic antagonist that helps treat angina and hypertension. The current study aimed to develop and validate the physiologically based pharmacokinetic model (PBPK) of nadolol in healthy adults, renal-compromised, and pediatric populations. A comprehensive...

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Hlavní autoři:	Samia Kalsoom, Muhammad Fawad Rasool, Imran Imran, Hamid Saeed, Tanveer Ahmad, Faleh Alqahtani
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2024-02-01
Edice:	Pharmaceuticals
Témata:	nadolol physiologically based pharmacokinetic PK-Sim pharmacokinetic renal impairment pediatrics
On-line přístup:	https://www.mdpi.com/1424-8247/17/2/265
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