A Comprehensive Physiologically Based Pharmacokinetic Model of Nadolol in Adults with Renal Disease and Pediatrics with Supraventricular Tachycardia

Nadolol is a long-acting non-selective β–adrenergic antagonist that helps treat angina and hypertension. The current study aimed to develop and validate the physiologically based pharmacokinetic model (PBPK) of nadolol in healthy adults, renal-compromised, and pediatric populations. A comprehensive...

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Principais autores:	Samia Kalsoom, Muhammad Fawad Rasool, Imran Imran, Hamid Saeed, Tanveer Ahmad, Faleh Alqahtani
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2024-02-01
Series:	Pharmaceuticals
Assuntos:	nadolol physiologically based pharmacokinetic PK-Sim pharmacokinetic renal impairment pediatrics
Acceso en liña:	https://www.mdpi.com/1424-8247/17/2/265
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