A Comprehensive Physiologically Based Pharmacokinetic Model of Nadolol in Adults with Renal Disease and Pediatrics with Supraventricular Tachycardia

Nadolol is a long-acting non-selective β–adrenergic antagonist that helps treat angina and hypertension. The current study aimed to develop and validate the physiologically based pharmacokinetic model (PBPK) of nadolol in healthy adults, renal-compromised, and pediatric populations. A comprehensive...

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Principais autores:	Samia Kalsoom, Muhammad Fawad Rasool, Imran Imran, Hamid Saeed, Tanveer Ahmad, Faleh Alqahtani
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2024-02-01
Serija:	Pharmaceuticals
Teme:	nadolol physiologically based pharmacokinetic PK-Sim pharmacokinetic renal impairment pediatrics
Online dostop:	https://www.mdpi.com/1424-8247/17/2/265
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