HSC70 coordinates COP9 signalosome and SCF ubiquitin ligase activity to enable a prompt stress response
Abstract The SCF (SKP1/CUL1/F-box protein) ubiquitin ligase complex plays a protective role against external stress, such as ultraviolet irradiation. The emergence of substrates activates SCF through neddylation, the covalent attachment of ubiquitin-like protein NEDD8 to CUL1. After substrate degrad...
שמור ב:
| Principais autores: | , , , , , , , , , , , , , |
|---|---|
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Springer Nature
2025-02-01
|
| סדרה: | EMBO Reports |
| נושאים: | |
| גישה מקוונת: | https://doi.org/10.1038/s44319-025-00376-x |
| תגים: |
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
|
