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Production of clinical grade patient iPSC-derived 3D retinal organoids containing transplantable photoreceptor cells

Abstract Background Neurodegenerative conditions that affect the retina are currently the leading cause of incurable blindness in the developed world. Although gene and drug therapies are being developed to slow disease progression in some cases, restorative cell replacement approaches are needed fo...

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Bibliografische gegevens
Hoofdauteurs: Laura R. Bohrer, Luke A. Wiley, Allison T. Wright, Bradley Hittle, Mallory J. Lang, Louisa M. Affatigato, Kimerly A. Powell, Lorena M. Haefeli, Ian C. Han, Robert F. Mullins, Edwin M. Stone, Budd A. Tucker
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMC 2025-11-01
Reeks:Stem Cell Research & Therapy
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Online toegang:https://doi.org/10.1186/s13287-025-04771-y
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