NR2E3 loss disrupts photoreceptor cell maturation and fate in human organoid models of retinal development
While dysfunction and death of light-detecting photoreceptor cells underlie most inherited retinal dystrophies, knowledge of the species-specific details of human rod and cone photoreceptor cell development remains limited. Here, we generated retinal organoids carrying retinal disease–causing varian...
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| Autores principales: | , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2024-06-01
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| Colección: | The Journal of Clinical Investigation |
| Materias: | |
| Acceso en línea: | https://doi.org/10.1172/JCI173892 |
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