SDHA loss of function mutations in a subset of young adult wild-type gastrointestinal stromal tumors

<p>Abstract</p> <p>Background</p> <p>A subset of KIT/PDGFRA wild-type gastrointestinal stromal tumors (WT GIST) have been associated with alteration of the succinate dehydrogenase (SDH) complex II function. A recent report identified four non-syndromic, KIT/PDGFRA WT GIST harboring compound heterozy...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Italiano Antoine, Chen Chun-Liang, Sung Yun-Shao, Singer Samuel, DeMatteo Ronald P, LaQuaglia Michael P, Besmer Peter, Socci Nicholas, Antonescu Cristina R
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2012-09-01
Edice:	BMC Cancer
Témata:	GIST Pediatric Wild-type SDHA SDHB Succinate dehydrogenase complex II
On-line přístup:	http://www.biomedcentral.com/1471-2407/12/408
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!