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Unveiling the hidden role of SDHA in breast cancer proliferation: a novel therapeutic avenue

Abstract Background We observed an increased presence of succinate dehydrogenase complex subunit A (SDHA), a mitochondrial enzyme, in breast cancer (BC), which contributes to its proliferation. While SDHA deficiency has been extensively researched in rare disorders, the upregulation of SDHA and its...

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Váldodahkkit: Liyun Yong, Yuan Fang, Lingli Jin, Xiuqin Zhang, Manuel A. Luis, Xiaoyan Lin, Shasha Tang, Fengfeng Cai
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: BMC 2025-03-01
Ráidu:Cancer Cell International
Fáttát:
Liŋkkat:https://doi.org/10.1186/s12935-025-03746-6
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