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SDH-deficient gastrointestinal stromal tumours

Gastrointestinal stromal tumours (GIST) comprise a heterogeneous group of the most common mesenchymal neoplasms of the gastrointestinal tract. The majority of GIST are induced by activating, mutually exclusive mutations of two genes – KIT and PDGFRA (platelet-derived growth factor receptor-alpha). H...

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Hoofdauteurs: Piotr Rutkowski, Katarzyna Seliga, Maria Dębiec-Rychter
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Via Medica 2022-10-01
Reeks:Nowotwory
Onderwerpen:
gastrointestinal stromal tumour
SDH-deficient GIST
Carney Triad
Carney-Stratakis syndrome
TKI
SDHA/SDHB/SDHC/SDHD mutations
targeted therapy
imatinib
regorafenib
Online toegang:https://journals.viamedica.pl/nowotwory_journal_of_oncology/article/view/91443
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