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SDHA loss of function mutations in a subset of young adult wild-type gastrointestinal stromal tumors

<p>Abstract</p> <p>Background</p> <p>A subset of KIT/PDGFRA wild-type gastrointestinal stromal tumors (WT GIST) have been associated with alteration of the succinate dehydrogenase (SDH) complex II function. A recent report identified four non-syndromic, KIT/PDGFRA WT GIST harboring compound heterozy...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Italiano Antoine, Chen Chun-Liang, Sung Yun-Shao, Singer Samuel, DeMatteo Ronald P, LaQuaglia Michael P, Besmer Peter, Socci Nicholas, Antonescu Cristina R
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2012-09-01
Rangatū:BMC Cancer
Ngā marau:
GIST
Pediatric
Wild-type
SDHA
SDHB
Succinate dehydrogenase complex II
Urunga tuihono:http://www.biomedcentral.com/1471-2407/12/408
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