DDR2 controls breast tumor stiffness and metastasis by regulating integrin mediated mechanotransduction in CAFs
Biomechanical changes in the tumor microenvironment influence tumor progression and metastases. Collagen content and fiber organization within the tumor stroma are major contributors to biomechanical changes (e., tumor stiffness) and correlated with tumor aggressiveness and outcome. What signals and...
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| Principais autores: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
eLife Sciences Publications Ltd
2019-05-01
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| Serier: | eLife |
| Fag: | |
| Online adgang: | https://elifesciences.org/articles/45508 |
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