NuA4 histone acetyltransferase activity is required for H4 acetylation on a dosage-compensated monosomic chromosome that confers resistance to fungal toxins

Abstract Background The major human fungal pathogen Candida albicans possesses a diploid genome, but responds to growth in challenging environments by employing chromosome aneuploidy as an adaptation mechanism. For example, we have shown that C. albicans adapts to growth on the toxic sugar l-sorbose...

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Autori principali:	Hironao Wakabayashi, Christopher Tucker, Gabor Bethlendy, Anatoliy Kravets, Stephen L. Welle, Michael Bulger, Jeffrey J. Hayes, Elena Rustchenko
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2017-10-01
Serie:	Epigenetics & Chromatin
Soggetti:	Candida albicans NuA4 H4 and H3 acetylation Chromosome 5 monosomy
Accesso online:	http://link.springer.com/article/10.1186/s13072-017-0156-y
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