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Mechanistic insights into histone recognition and H3K14 acetylation by the NuA3 histone acetyltransferase complex

Abstract The NuA3 histone acetyltransferase complex in budding yeast, composed of six subunits, specifically acetylates lysine 14 on histone H3 (H3K14), thereby regulating various biological processes. Despite its importance, the structural basis and mechanism underlying histone tail recognition and...

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Principais autores: Wenping Shi, Lixia Zhao, Yiru Wang, Yi Zhang, Simiao Liu, Yannan Wang, Roger D. Kornberg, Heqiao Zhang
Format: Artigo
Jezik:Inglês
Izdano: Nature Portfolio 2025-11-01
Serija:Nature Communications
Online dostop:https://doi.org/10.1038/s41467-025-67049-0
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