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The NuA4 acetyltransferase and histone H4 acetylation promote replication recovery after topoisomerase I-poisoning

Abstract Background Histone acetylation plays an important role in DNA replication and repair because replicating chromatin is subject to dynamic changes in its structures. However, its precise mechanism remains elusive. In this report, we describe roles of the NuA4 acetyltransferase and histone H4...

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Tallennettuna:
Päätekijät: Chiaki Noguchi, Tanu Singh, Melissa A. Ziegler, Jasmine D. Peake, Lyne Khair, Ana Aza, Toru M. Nakamura, Eishi Noguchi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BMC 2019-04-01
Sarja:Epigenetics & Chromatin
Aiheet:
Histone H4
Acetylation
DNA replication
Replication forks
Chromatin
Schizosaccharomyces pombe
Linkit:http://link.springer.com/article/10.1186/s13072-019-0271-z
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