NuA4 histone acetyltransferase activity is required for H4 acetylation on a dosage-compensated monosomic chromosome that confers resistance to fungal toxins

Abstract Background The major human fungal pathogen Candida albicans possesses a diploid genome, but responds to growth in challenging environments by employing chromosome aneuploidy as an adaptation mechanism. For example, we have shown that C. albicans adapts to growth on the toxic sugar l-sorbose...

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Principais autores:	Hironao Wakabayashi, Christopher Tucker, Gabor Bethlendy, Anatoliy Kravets, Stephen L. Welle, Michael Bulger, Jeffrey J. Hayes, Elena Rustchenko
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2017-10-01
coleção:	Epigenetics & Chromatin
Assuntos:	Candida albicans NuA4 H4 and H3 acetylation Chromosome 5 monosomy
Acesso em linha:	http://link.springer.com/article/10.1186/s13072-017-0156-y
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