Depletion of Demethylase KDM6 Enhances Early Neuroectoderm Commitment of Human PSCs

Epigenetic modifications play a crucial role in neurogenesis, learning, and memory, but the study of their role in early neuroectoderm commitment from pluripotent inner cell mass is relatively lacking. Here we utilized the system of directed neuroectoderm differentiation from human embryonic stem ce...

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Autors principals:	Yajing Meng, Tianzhe Zhang, Ran Zheng, Song Ding, Jie Yang, Ran Liu, Yingan Jiang, Wei Jiang
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2021-09-01
Col·lecció:	Frontiers in Cell and Developmental Biology
Matèries:	KDM6 neuroectoderm differentiation human embryonic stem cell GSK-J1 KDM6A KDM6B
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fcell.2021.702462/full
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