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The Diverse Roles of Histone Demethylase KDM4B in Normal and Cancer Development and Progression

Histone methylation status is an important process associated with cell growth, survival, differentiation and gene expression in human diseases. As a member of the KDM4 family, KDM4B specifically targets H1.4K26, H3K9, H3K36, and H4K20, which affects both histone methylation and gene expression. The...

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Bibliografiske detaljer
Principais autores: Zhongze Wang, Huarui Cai, Erhu Zhao, Hongjuan Cui
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2022-02-01
Serier:Frontiers in Cell and Developmental Biology
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Online adgang:https://www.frontiersin.org/articles/10.3389/fcell.2021.790129/full
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